Biodesign® – Otologic Tissue Repair Graft

Advanced Tissue Repair

The ideal Otological Surgical Reinforcement Graft for Myringoplasty, Tympanoplasty and Mastoidectomy


Biodesign® is a platform technology behind numerous tissue-repair products that span multiple medical specialties. Biodesign is natural extracellular matrix (ECM) derived from porcine small intestinal submucosa (SIS). The ECM is a complex latticework of proteins and structural molecules that helps guide the growth of cells.

Cook’s proprietary processing methodology decellularizes the SIS material while preserving natural matrix molecules such as collagen, proteoglycans, and glycosaminoglycans. The result is a scaffold that, when implanted, provides a location for host cells to infiltrate and remodel into vascularized tissue.

The Biodesign Otologic Repair Graft is a grafting biomaterial for tympanic membrane perforation closure. It provides the surgeon with a truly minimally invasive approach to ear surgery with no donor site required and thus no additional scar for the patient.






Biodesign material is easy to manipulate, allowing for improved precision during graft placement. The convenient sizing and packaging help simplify closures. The circular size options come with a case, and the square sheet sizes can be cut to a preferred size and shape.

The Biodesign Otologic Repair Graft offers a complete closure with neovascularisation and avoids additional comorbidities and scarring associated with the harvest of patient tissue.

Sizes & Ordering information
Biodesign Otologic Repair Graft
Order NumberReference Part NumberSize cmNominal Thickness mm
G58272ENT-OTO-0.6-0.9-20.6, 0.90.25
G58273ENT-OTO-2.5×2.5-22.5 x 2.50.25
G58274ENT-OTO-5×5-25 x 50.25

For further details the Biodesign ENT OTO brochure can seen here

Alternatively, contact us via the Info Request form.

  • D’Eredità R. Porcine small intestinal submucosa (SIS) myringoplasty in children: a randomized controlled study. Int J Pediatr Otorhinolaryngol. 2015;79(7):1085-1089.
  • James AL. Endoscope or microscope-guided pediatric tympanoplasty? Comparison of grafting technique and outcome. Laryngoscope. 2017;127(11):2659-2664.
  • Yawn RJ, Dedmon MM, O’Connell BP, et al. Tympanic membrane perforation repair using
    porcine small intestinal submucosal grafting. Otol Neurotol. 2018;39(5):e332–e335. 3.
  • Redaelli De Zinis LO, Berlucchi M, Nassif N. Double-handed endoscopic myringoplasty with a holding system in children: preliminary observations. Int J Pediatr Otorhinolaryngol. 2017;96:127–130.


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