Biodesign® – Dural Repair & Duraplasty Grafts

Biodesign Advanced Tissue Repair – handle with ease, repair with confidence
  • Providing a strong seal
  • Excellent handling
  • Sutured/Sutureless fixation

Description

Biodesign® is a platform technology behind numerous tissue-repair products that span multiple medical specialties. Biodesign is natural extracellular matrix (ECM) derived from porcine small intestinal submucosa (SIS). The ECM is a complex latticework of proteins and structural molecules that helps guide the growth of cells.

Cook’s proprietary processing methodology decellularizes the SIS material while preserving natural matrix molecules such as collagen, proteoglycans, and glycosaminoglycans. The result is a scaffold that, when implanted, provides a location for host cells to infiltrate and remodel into vascularized tissue.

Biodesign Dural Repair

The Biodesign Dural Repair Graft is used as a dural substitute for repairing dura mater, it is easy for the surgeon to manipulate, doesn’t swell with hydration and doesn’t fold onto itself. Once placed it provides a strong seal and is completely remodelled into natural host tissue, with post-op leaks as low as 1.7% reported.

Tips to help get the best results include;

  • Ensure adequate blood supply
  • Size the graft to allow tissue overlap
  • Hydrate for at least 2 minutes before placement
Sizes and ordering information – Dural Repair Graft
Order Number Reference Part Number Size CM Nominal Thickness
G57557 C-DUR-2X3-2 2 x 3 0.25
G57558 C-DUR-4X7-2 4 x 7 0.25
G57559 C-DUR-7X10-2 7 x 10 0.25
G57560 C-DUR-7X20-2 7 x 20 0.25

Biodesign Duraplasty Graft

The Biodesign Duraplasty Graft is indicated for use as a dura substitute for the repair of dura mater. This graft is supplied sterile in peel-open packages and is intended for one-time use.

It shares the same characteristics as the rest of the Biodesign range and in this indication it is used as an onlay graft that can be secured in place with or without sutures, depending on clinician preference.

Surgical Video – Skull base reconstruction
Sizes and ordering information – Duraplasty Graft
Order Number Reference Part Number Size CM Nominal Thickness
G57553 ENT-CBD-1X2-2 1 x 2 0.25
G57554 ENT-CBD-2.5X2.5-2 2.5 x 2.5 0.25
G57555 ENT-CBD-5X5-2 5 x 5 0.25
G57556 ENT-CBD-7X8.5-2 7 x 8.5 0.25

For further details on the Biodesign Dural/Duraplasty range you can view the family brochure here

Alternatively, contact us via the Info Request form.

References
  • Bejjani GK, Zabramski J; Durasis Study Group. Safety and efficacy of the porcine small intestinal submucosa dural substitute: results of a prospective multicenter study and literature review. J Neurosurg. 2007;106(6):1028-1033.
  • Hubbell JA. Materials as morphogenetic guides in tissue engineering. Curr Opin Biotechnol. 2003;14:551-558.
  • Hodde J, Janis A, Ernst D, Zopf D, Sherman D, Johnson C. Effects of sterilization on an extracellular matrix scaffold: Part I. Composition and matrix architecture. J Mater Sci Mater Med. 2007;18(4):537-543.
  • Illing E, Chaaban MR, Riley KO, Woodworth BA. Porcine small intestine submucosal graft for
    endoscopic skull base reconstruction. Int Forum Allergy Rhinol. 2013;3(11):928-932.

 

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